Malawi's health officials have identified a sixth case of Mpox, heightening concerns over an outbreak that began just two weeks ago. A situational report issued on May 1 by the Public Health Institute of Malawi (PHIM) confirmed the latest case, an 18-year-old male student from Area 36, Tumbwe, in Lilongwe District. The student sought medical attention at Bwaila Hospital on April 30 after presenting with typical Mpox symptoms, including fever, fatigue, shortness of breath, and a distinctive skin rash. Laboratory analysis subsequently verified the infection. Although the patient had not traveled recently, he had close contact with a previously confirmed case, underscoring ongoing local transmission. This newest infection raises the country’s total to six, all recorded in Lilongwe, a concerning indication of possible community spread in Malawi’s most densely populated urban area. Mpox, formerly referred to as monkeypox, is a viral zoonotic disease caused by the monkeypox virus, closely related to the virus responsible for smallpox. Transmission mainly occurs through direct physical contact with infected individuals, animals, or contaminated materials like clothing and bedding.