Holders, Liverpool have been drawn against Atletico Madrid while EPL champions Manchester City will face Real Madrid in the last 16 of the Champions League.
Frank Lampard Blues will take on Bayern Munich in a repeat of the 2012 final won by Chelsea while Jose Mourinho Tottenham faces RB Leipzig.
The first legs will be played on 18, 19, 25 and 26 February with the return matches on 10, 11, 17 and 18 March.
This season final is on 30 May at the Ataturk Stadium in Istanbul, the ground where Liverpool won the epic 2005 match against AC Milan.
Last-16 Draw in full
Borussia Dortmund v Paris St-Germain
Real Madrid v Manchester City
Atalanta v Valencia
Atletico Madrid v Liverpool
Chelsea v Bayern Munich
Lyon v Juventus
Tottenham v RB Leipzig
Napoli v Barcelona
